How is it that your body with all of its specialized organs developed from a single cell? Scientists are exploring how gene expression patterns and their timing regulate cell differentiation. Today, ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

A team at Johns Hopkins Medicine has focused their work on myelin development using oligodendrocytes to help study conditions like MS.

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Thymalin is a polypeptide complex derived from thymic preparations (often of bovine or calf origin), known to harbor among ...

Several clinical trials are testing to inhibit the LSD1 protein's ability to modify gene expression. However, the study shows that LSD1 not only affects gene expression in the way previously assumed ...

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one ...

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the ...

New evidence shows that precursors of myelin-producing cells — one of the few #brain cell types that continue to be produced ...