Caribou Biosciences, Inc. experienced a 45% share price decline after presenting puzzling results for their product candidate CB-010 in a Phase 1 clinical trial. CB-010 showed limited efficacy in ...

HLA matching in bone marrow transplantation has an important role in determining successful outcome. However HLA typing of both potential related and unrelated donors can be both time-consuming and ...

Jayme Locke, MD MARCO ISLAND, Fla.—The transplant community may want to rethink the importance of HLA mismatches when considering live donor kidney transplants, according to new data presented here at ...

HLA compatibility is considered the key criterion for selecting donors for allo-HSCT. DKMS study data presented at the DGHO Annual Meeting 2025 in Cologne indicate the biological age of donors has a ...

ORLANDO -- Stem-cell transplants with mismatched unrelated donors (MMUDs) beyond a single HLA locus (<7/8) had 1-year survival similar to better-matched donors, suggesting significant potential to ...

Analyses of two large stem-cell transplant registries yielded conflicting results about the effect of post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis on the ...

Anil Paramesh, MD De-emphasis on HLA matching could lead to worse outcomes in highly sensitized patients, FORT LAUDERDALE, Fla.—Highly sensitized renal transplant recipients can have excellent ...

CHICAGO, Oct. 11, 2023 /PRNewswire/ -- In the near future, HLA typing is poised to revolutionize the transplant industry. Rapid advancements in genomics and precision medicine will enable transplant ...