By examining genetic clues that linger in adult cells, scientists have now gained surprising insights into the developmental ...

It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage ...

PAX6-dependent epithelial differentiation and developmental trajectories of the ocular surface are elucidated through single-cell RNA sequencing of hiPSC-derived ocular organoids. This study provides ...

Collaborative work has developed a cell culture system that differentiates human pluripotent stem cells to amniotic ectoderm and surface ectoderm based on cell density. Research conducted by Dr Shota ...

Researchers investigating a widely used medication have uncovered an unexpected cellular process that may interfere with ...

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical ...

A new platform for studying mtDNA mutations implicated in human disease could help accelerate treatments for mitochondrial ...

The discovery of a gene essential to early embryonic development sheds light on the preliminary stages of human placenta formation. A team led by scientists from the University of California San Diego ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...