Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

A newly identified brain pathway in mice could explain why placebos, or interventions designed to have no therapeutic effect, still relieve pain. Developing drugs that target this pathway may lead to ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

Researchers at UC Santa Barbara identified a pain pathway in fruit flies that reduces the sensation of pain from heat. The researchers discovered that just a single neuron on each side of the animal’s ...

Share on Pinterest Researchers say circuits in the brain could help provide pain relief without the use of opioids. Westend61/Getty Images Researchers have identified an alternative pain control ...

Researchers describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side effects. In a study published in Science, researchers at ...

Three floors below Dmitriy Sheyn’s lab at Cedars-Sinai Medical Center, doctors remove degenerated intervertebral discs from patients with severe back pain. Instead of tossing the old discs, however, ...

Women’s greater susceptibility to gastrointestinal pain may be rooted in hormonal activity, with new research pointing to ...

PITTSBURGH (KDKA) — For the first time in western Pennsylvania and possibly in the nation, patients at a local hospital can choose not to be given opioids before, during and after surgeries. Inside ...