Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three antihypertensive drugs at low doses, in addition to standard antihypertensive ...

The Pediatric Research Equity Act was intended to promote the development and testing of prescription drugs for children. But ...

Post-thrombotic syndrome is common after deep-vein thrombosis and can cause severe symptoms involving the limbs that impair patients’ activity and quality of life. Endovascular therapy can ...

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 5).

A 16-year-old girl presented with 1 month of ankle pain and 11 days of fever. Radiographs showed an ill-defined, radiolucent distal tibial lesion; on MRI, the lesion was hypointense and surrounded by ...

Owing to the fact that most thromboembolic complications that are attributed to atrial fibrillation originate in the left atrial appendage, 1 therapies targeting the anatomical structure that might ...

Abstract In this second of two Health Policy Reports marking the 10th anniversary of the Affordable Care Act, the authors describe major payment and delivery system reforms and analyze the available ...

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 2).

A 21-year-old woman presented with abdominal pain and constipation and was found to have hypertension with renal failure. Imaging showed an obstructive mass.

A 27-year-old woman presented with a 2-week history of joint pain, fever, sore throat, and a nonpruritic rash that worsened during fever. Laboratory tests showed an elevated ESR and elevated ...

An 18-year-old man presented to the emergency department with generalized tonic–clonic seizures. MRI of the head showed numerous well-defined cystic lesions in the brain that were consistent with ...

Health worker burnout, exacerbated by Covid-19, is not only about long hours. It’s about the fundamental disconnect between health workers and the mission to serve that motivates them.