This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...
BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
A375, HEK293T, Sk-Mel-3 and Sk-Mel-24 cell lines were obtained from the American Type Culture Collection. A375 and HEK293T cells were maintained in ...