First-time use of AI for genetic circuit design demonstrated in a human cell line

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...
eLife

A novel high-throughput single-cell DNA sequencing method reveals hidden genomic heterogeneity in the unicellular eukaryote Leishmania

This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...
Bay News 9

Almost 200 snakes removed during this year's python challenge

DUCK KEY, Fla. — The Florida Fish and Wildlife Conservation Commission (FWC) is celebrating what it calls a successful Python Challenge and announcing its 2024 winners. This year, 857 participants ...
eLife

Conformational Variability of HIV-1 Env Trimer and Viral Vulnerability

In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.